BDBM50210206 4-(2-(aminomethyl)phenyl)-1-(dio-tolylmethyl)piperidin-4-ol::CHEMBL400035

SMILES Cc1ccccc1C(N1CCC(O)(CC1)c1ccccc1CN)c1ccccc1C

InChI Key InChIKey=ZUCAHKWKUIULAI-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50210206   

TargetNociceptin receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50210206(4-(2-(aminomethyl)phenyl)-1-(dio-tolylmethyl)piper...)
Affinity DataKi:  0.5nMAssay Description:Displacement of [125I][Tyr14]nociceptin FQ from human NOP receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50210206(4-(2-(aminomethyl)phenyl)-1-(dio-tolylmethyl)piper...)
Affinity DataKi:  190nMAssay Description:Displacement of [3H]diprenorphine from human MOP receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50210206(4-(2-(aminomethyl)phenyl)-1-(dio-tolylmethyl)piper...)
Affinity DataKi:  450nMAssay Description:Displacement of [3H]diprenorphine from human KOP receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50210206(4-(2-(aminomethyl)phenyl)-1-(dio-tolylmethyl)piper...)
Affinity DataKi:  8.44E+3nMAssay Description:Displacement of [3H]diprenorphine from human DOP receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed