BDBM50210221 1-(bis(2-chlorophenyl)methyl)-4-(2-(piperazin-1-ylmethyl)phenyl)piperidin-4-ol::CHEMBL232075

SMILES OC1(CCN(CC1)C(c1ccccc1Cl)c1ccccc1Cl)c1ccccc1CN1CCNCC1

InChI Key InChIKey=ROLCHVRRPRQQIU-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50210221   

TargetNociceptin receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50210221(1-(bis(2-chlorophenyl)methyl)-4-(2-(piperazin-1-yl...)
Affinity DataKi:  1.90nMAssay Description:Displacement of [125I][Tyr14]nociceptin FQ from human NOP receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50210221(1-(bis(2-chlorophenyl)methyl)-4-(2-(piperazin-1-yl...)
Affinity DataKi:  145nMAssay Description:Displacement of [3H]diprenorphine from human MOP receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50210221(1-(bis(2-chlorophenyl)methyl)-4-(2-(piperazin-1-yl...)
Affinity DataKi:  261nMAssay Description:Displacement of [3H]diprenorphine from human KOP receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50210221(1-(bis(2-chlorophenyl)methyl)-4-(2-(piperazin-1-yl...)
Affinity DataKi:  1.17E+3nMAssay Description:Displacement of [3H]diprenorphine from human DOP receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed