BDBM50210241 1-benzhydryl-4-(3-methylthiophen-2-yl)piperidin-4-ol::CHEMBL393356

SMILES Cc1ccsc1C1(O)CCN(CC1)C(c1ccccc1)c1ccccc1

InChI Key InChIKey=GGAITJRZAAULQE-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50210241   

TargetNociceptin receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50210241(1-benzhydryl-4-(3-methylthiophen-2-yl)piperidin-4-...)
Affinity DataKi:  15nMAssay Description:Displacement of [125I][Tyr14]nociceptin FQ from human NOP receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50210241(1-benzhydryl-4-(3-methylthiophen-2-yl)piperidin-4-...)
Affinity DataKi:  756nMAssay Description:Displacement of [3H]diprenorphine from human MOP receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50210241(1-benzhydryl-4-(3-methylthiophen-2-yl)piperidin-4-...)
Affinity DataKi:  2.57E+3nMAssay Description:Displacement of [3H]diprenorphine from human KOP receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50210241(1-benzhydryl-4-(3-methylthiophen-2-yl)piperidin-4-...)
Affinity DataKi:  8.89E+3nMAssay Description:Displacement of [3H]diprenorphine from human DOP receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed