BDBM50211166 1-(3-methoxy-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-3-(4-phenoxyphenyl)imidazolidine-2,4-dione::CHEMBL246794

SMILES COc1cc(ccc1OCCN1CCCC1)-n1cc(O)n(-c2ccc(Oc3ccccc3)cc2)c1=O

InChI Key InChIKey=PAXJABBAIBFJBH-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50211166   

LigandPNGBDBM50211166(1-(3-methoxy-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-...)
Affinity DataKi:  164nMAssay Description:Displacement of [125I][Phe13, Tyr19]MCH from human recombinant MCHR1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50211166(1-(3-methoxy-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-...)
Affinity DataKi:  164nMAssay Description:Antagonist activity at MCH1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Cerep

Curated by ChEMBL
LigandPNGBDBM50211166(1-(3-methoxy-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-...)
Affinity DataKi:  330nMAssay Description:Binding affinity to 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Cerep

Curated by ChEMBL
LigandPNGBDBM50211166(1-(3-methoxy-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-...)
Affinity DataKi:  370nMAssay Description:Binding affinity to muscarinic M1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Cerep

Curated by ChEMBL
LigandPNGBDBM50211166(1-(3-methoxy-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-...)
Affinity DataKi:  880nMAssay Description:Binding affinity to 5HT2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed