BDBM50211510 CHEMBL3946274

SMILES NS(=O)(=O)c1ccc(NC(=O)c2c(NC(=O)c3ccc(Cl)cc3)onc2-c2ccc(Cl)cc2Cl)cc1

InChI Key InChIKey=DEHGMOVCXVWKNW-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50211510   

TargetCarbonic anhydrase 7(Human)
Abant Izzet Baysal University

Curated by ChEMBL
LigandPNGBDBM50211510(CHEMBL3946274)
Affinity DataKi:  55nMAssay Description:Inhibition of recombinant human carbonic anhydrase 7 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2018
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Human)
Abant Izzet Baysal University

Curated by ChEMBL
LigandPNGBDBM50211510(CHEMBL3946274)
Affinity DataKi:  80nMAssay Description:Inhibition of recombinant human carbonic anhydrase 4 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2018
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Abant Izzet Baysal University

Curated by ChEMBL
LigandPNGBDBM50211510(CHEMBL3946274)
Affinity DataKi:  350nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2018
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Abant Izzet Baysal University

Curated by ChEMBL
LigandPNGBDBM50211510(CHEMBL3946274)
Affinity DataKi:  3.94E+3nMAssay Description:Inhibition of recombinant human carbonic anhydrase 1 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2018
Entry Details Article
PubMed