BDBM50211982 CHEMBL234010::N-(4-chlorophenyl)-3-methyl-1-(2-(pyridin-4-yl)ethyl)-1Hpyrazole-5-carboxamide

SMILES Cc1cc(C(=O)Nc2ccc(Cl)cc2)n(CCc2ccncc2)n1

InChI Key InChIKey=JLBOPYOYNAUDRW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50211982   

TargetVascular endothelial growth factor receptor 2(Human)
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50211982(N-(4-chlorophenyl)-3-methyl-1-(2-(pyridin-4-yl)eth...)
Affinity DataIC50: 780nMAssay Description:Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50211982(N-(4-chlorophenyl)-3-methyl-1-(2-(pyridin-4-yl)eth...)
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50211982(N-(4-chlorophenyl)-3-methyl-1-(2-(pyridin-4-yl)eth...)
Affinity DataIC50: 2.54E+3nMAssay Description:Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed