BDBM50212509 3-fluoro-4'-[7-methoxy-6-(4-methyl-piperazin-1-ylmethyl)-1,4-dihydro-indeno[1,2-c]pyrazol-3-yl]-biphenyl-4-ol::CHEMBL233831

SMILES COc1cc-2c(Cc3c(n[nH]c-23)-c2ccc(cc2)-c2ccc(O)c(F)c2)cc1CN1CCN(C)CC1

InChI Key InChIKey=OKZVFXHUQZQGPK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50212509   

TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50212509(3-fluoro-4'-[7-methoxy-6-(4-methyl-piperazin-1-ylm...)
Affinity DataIC50: 28nMAssay Description:Inhibition of recombinant CHK-mediated Cdc25C phosphorylation after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed