BDBM50212512 3-(4'-hydroxy-biphenyl-4-yl)-1,4-dihydro-indeno[1,2-c]pyrazole-6-carboxylic acid (pyridin-2-ylmethyl)-amide::CHEMBL234479

SMILES Oc1ccc(cc1)-c1ccc(cc1)-c1n[nH]c-2c1Cc1cc(ccc-21)C(=O)NCc1ccccn1

InChI Key InChIKey=GALUBKKRBHABCT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50212512   

TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50212512(3-(4'-hydroxy-biphenyl-4-yl)-1,4-dihydro-indeno[1,...)
Affinity DataIC50: 9.30nMAssay Description:Inhibition of recombinant CHK-mediated Cdc25C phosphorylation after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed