BDBM50212520 CHEMBL444630::[3-(4'-hydroxy-biphenyl-4-yl)-7-methoxy-1,4-dihydro-indeno[1,2-c]pyrazol-6-yl]-(4-methyl-piperazin-1-yl)-methanone

SMILES COc1cc-2c(Cc3c(n[nH]c-23)-c2ccc(cc2)-c2ccc(O)cc2)cc1C(=O)N1CCN(C)CC1

InChI Key InChIKey=LSBCHUAQXSUNOI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50212520   

TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50212520([3-(4'-hydroxy-biphenyl-4-yl)-7-methoxy-1,4-dihydr...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of recombinant CHK-mediated Cdc25C phosphorylation after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed