BDBM50213310 2-(6-(2-((4-(trifluoromethyl)phenoxy)methyl)benzyloxy)-5-methylbenzo[b]thiophen-3-yl)acetic acid::CHEMBL234587

SMILES Cc1cc2c(CC(O)=O)csc2cc1OCc1ccccc1COc1ccc(cc1)C(F)(F)F

InChI Key InChIKey=YDNAXUMKGRAZTP-UHFFFAOYSA-N

Data  6 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50213310   

LigandPNGBDBM50213310(2-(6-(2-((4-(trifluoromethyl)phenoxy)methyl)benzyl...)
Affinity DataIC50: 7.58E+3nMAssay Description:Displacement of [3H]5-(4-(3-(5-methyl-2-phenyloxazol-4-yl)propanoyl)benzyl)thiazolidine-2,4-dione from human PPARgamma after 2 hrs by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50213310(2-(6-(2-((4-(trifluoromethyl)phenoxy)methyl)benzyl...)
Affinity DataIC50: 4.68E+3nMAssay Description:Displacement of [3H]2-(4-(2-(3-(2,4-difluorophenyl)-1-heptylureido)ethyl)phenoxy)-2-methylbutanoic acid from human PPARalpha after 30 mins by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50213310(2-(6-(2-((4-(trifluoromethyl)phenoxy)methyl)benzyl...)
Affinity DataEC50:  172nMAssay Description:Agonist activity at human PPARdelta in HepG2 cells by GAL4-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50213310(2-(6-(2-((4-(trifluoromethyl)phenoxy)methyl)benzyl...)
Affinity DataIC50: 43nMAssay Description:Displacement of [3H]2-(4-(3-(4-acetyl-3-hydroxy-2 propyl-phenoxy)propoxy)phenoxy)acetic acid from human PPARdelta after 30 mins by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50213310(2-(6-(2-((4-(trifluoromethyl)phenoxy)methyl)benzyl...)
Affinity DataIC50: 43.0nMAssay Description:Agonist activity at PPARdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50213310(2-(6-(2-((4-(trifluoromethyl)phenoxy)methyl)benzyl...)
Affinity DataIC50: 7.59E+3nMAssay Description:Agonist activity at PPARgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50213310(2-(6-(2-((4-(trifluoromethyl)phenoxy)methyl)benzyl...)
Affinity DataIC50: 4.68E+3nMAssay Description:Agonist activity at PPARalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed