BDBM50213527 CHEMBL228390::N-((1r,4r)-4-(4-(2-(2,2,2-trifluoroethoxy)phenyl)piperidin-1-yl)cyclohexyl)-2,3-dihydrobenzo[b][1,4]dioxine-6-sulfonamide

SMILES FC(F)(F)COc1ccccc1C1CCN(CC1)[C@H]1CC[C@@H](CC1)NS(=O)(=O)c1ccc2OCCOc2c1

InChI Key InChIKey=PPAIEDLGYFCKEB-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50213527   

TargetAlpha-1A adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50213527(N-((1r,4r)-4-(4-(2-(2,2,2-trifluoroethoxy)phenyl)p...)
Affinity DataKi:  2.20nMAssay Description:Binding affinity to human cloned adrenergic alpha-1a receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50213527(N-((1r,4r)-4-(4-(2-(2,2,2-trifluoroethoxy)phenyl)p...)
Affinity DataKi:  23nMAssay Description:Binding affinity for dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50213527(N-((1r,4r)-4-(4-(2-(2,2,2-trifluoroethoxy)phenyl)p...)
Affinity DataKi:  26nMAssay Description:Binding affinity to human cloned adrenergic alpha-1d receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50213527(N-((1r,4r)-4-(4-(2-(2,2,2-trifluoroethoxy)phenyl)p...)
Affinity DataKi:  91nMAssay Description:Binding affinity to human cloned adrenergic alpha-1b receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed