BDBM50213532 CHEMBL228608::N-((1s,4s)-4-(4-(4-fluoro-2-isopropoxyphenyl)piperidin-1-yl)cyclohexyl)-3,4-dimethoxybenzenesulfonamide

SMILES COc1ccc(cc1OC)S(=O)(=O)N[C@H]1CC[C@H](CC1)N1CCC(CC1)c1ccc(F)cc1OC(C)C

InChI Key InChIKey=FEQSGCAJKJDTEE-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50213532   

TargetAlpha-1D adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50213532(N-((1s,4s)-4-(4-(4-fluoro-2-isopropoxyphenyl)piper...)
Affinity DataKi:  12nMAssay Description:Binding affinity to human cloned adrenergic alpha-1d receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50213532(N-((1s,4s)-4-(4-(4-fluoro-2-isopropoxyphenyl)piper...)
Affinity DataKi:  16nMAssay Description:Binding affinity to human cloned adrenergic alpha-1a receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50213532(N-((1s,4s)-4-(4-(4-fluoro-2-isopropoxyphenyl)piper...)
Affinity DataKi:  106nMAssay Description:Binding affinity for dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50213532(N-((1s,4s)-4-(4-(4-fluoro-2-isopropoxyphenyl)piper...)
Affinity DataKi:  690nMAssay Description:Binding affinity to human cloned adrenergic alpha-1b receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed