BDBM50213668 (S)-2-(2-(3,5-dimethylphenyl)-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridin-3-yl)-N-(2-(pyridin-4-yl)ethyl)propan-1-amine::CHEMBL233761

SMILES C[C@H](CNCCc1ccncc1)c1c2CNCCc2[nH]c1-c1cc(C)cc(C)c1

InChI Key InChIKey=CGMXRZJAQKSMCY-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50213668   

TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50213668((S)-2-(2-(3,5-dimethylphenyl)-4,5,6,7-tetrahydro-1...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human GnRHR expressed in RBL cells assessed as inhibition of GnRH-stimulated [3H]inositol phosphate hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50213668((S)-2-(2-(3,5-dimethylphenyl)-4,5,6,7-tetrahydro-1...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]-Tyr5, DLeu6, NMeLeu7, Pro-N-Et-GnRH from cloned rat GnRHRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed