BDBM50213939 1-(benzylsulfonyl)-3-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydroxypiperidine-3-carboxamide::CHEMBL250709

SMILES CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCCN(C1)S(=O)(=O)Cc1ccccc1)C(=O)NO

InChI Key InChIKey=ZXFJUXBYVRDBQU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50213939   

LigandPNGBDBM50213939(1-(benzylsulfonyl)-3-((4-(but-2-ynyloxy)phenylsulf...)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of TACE by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50213939(1-(benzylsulfonyl)-3-((4-(but-2-ynyloxy)phenylsulf...)
Affinity DataIC50: 260nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50213939(1-(benzylsulfonyl)-3-((4-(but-2-ynyloxy)phenylsulf...)
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed