BDBM50213950 3-((4-(but-2-ynylamino)phenylsulfonyl)methyl)-N-hydroxy-1-(isopropylsulfonyl)piperidine-3-carboxamide::CHEMBL250907

SMILES CC#CCNc1ccc(cc1)S(=O)(=O)CC1(CCCN(C1)S(=O)(=O)C(C)C)C(=O)NO

InChI Key InChIKey=RZAVXBHMHDOVTM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50213950   

LigandPNGBDBM50213950(3-((4-(but-2-ynylamino)phenylsulfonyl)methyl)-N-hy...)
Affinity DataIC50: 18nMAssay Description:Inhibition of TACE by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50213950(3-((4-(but-2-ynylamino)phenylsulfonyl)methyl)-N-hy...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50213950(3-((4-(but-2-ynylamino)phenylsulfonyl)methyl)-N-hy...)
Affinity DataIC50: 1.67E+4nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed