BDBM50213957 CHEMBL446456::ethyl 3-((4-(but-2-ynylamino)phenylsulfonyl)methyl)-3-(hydroxycarbamoyl)piperidine-1-carboxylate

SMILES CCOC(=O)N1CCCC(CS(=O)(=O)c2ccc(NCC#CC)cc2)(C1)C(=O)NO

InChI Key InChIKey=UAIMSPBCAMKARB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50213957   

LigandPNGBDBM50213957(ethyl 3-((4-(but-2-ynylamino)phenylsulfonyl)methyl...)
Affinity DataIC50: 21nMAssay Description:Inhibition of TACE by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50213957(ethyl 3-((4-(but-2-ynylamino)phenylsulfonyl)methyl...)
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50213957(ethyl 3-((4-(but-2-ynylamino)phenylsulfonyl)methyl...)
Affinity DataIC50: 1.67E+4nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed