BDBM50214098 CHEMBL401064::N-((2-(5-(isoquinolin-4-yl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-1H-benzo[d]imidazol-4-yl)methyl)propan-2-amine

SMILES CC(C)NCc1cccc2nc([nH]c12)-c1n[nH]c2ncc(cc12)-c1cncc2ccccc12

InChI Key InChIKey=NTRCIHPFGKPYRR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50214098   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50214098(N-((2-(5-(isoquinolin-4-yl)-1H-pyrazolo[3,4-b]pyri...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50214098(N-((2-(5-(isoquinolin-4-yl)-1H-pyrazolo[3,4-b]pyri...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50214098(N-((2-(5-(isoquinolin-4-yl)-1H-pyrazolo[3,4-b]pyri...)
Affinity DataIC50: 13nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50214098(N-((2-(5-(isoquinolin-4-yl)-1H-pyrazolo[3,4-b]pyri...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of RETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed