BDBM50214530 4-[2,4-dioxo-5-(4-phenoxybenzylidene)thiazolidin-3-yl]methylbenzoic acid::CHEMBL393606

SMILES OC(=O)c1ccc(CN2C(=O)S\C(=C/c3ccc(Oc4ccccc4)cc3)C2=O)cc1

InChI Key InChIKey=MAKLPSKEADWFJA-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50214530   

TargetLow molecular weight phosphotyrosine protein phosphatase(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50214530(4-[2,4-dioxo-5-(4-phenoxybenzylidene)thiazolidin-3...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human low molecular weight Protein-tyrosine phosphatase IF2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50214530(4-[2,4-dioxo-5-(4-phenoxybenzylidene)thiazolidin-3...)
Affinity DataIC50: 2.46E+4nMAssay Description:Inhibition of human leukocyte antigen related protein-tyrosine phosphataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50214530(4-[2,4-dioxo-5-(4-phenoxybenzylidene)thiazolidin-3...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human protein-tyrosine phosphatase betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50214530(4-[2,4-dioxo-5-(4-phenoxybenzylidene)thiazolidin-3...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human T cell protein-tyrosine phosphataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Baker's yeast)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50214530(4-[2,4-dioxo-5-(4-phenoxybenzylidene)thiazolidin-3...)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of Saccharomyces cerevisiae low molecular weight Protein-tyrosine phosphatase Ltp1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50214530(4-[2,4-dioxo-5-(4-phenoxybenzylidene)thiazolidin-3...)
Affinity DataIC50: 900nMAssay Description:Inhibition of human low molecular weight Protein-tyrosine phosphatase IF1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50214530(4-[2,4-dioxo-5-(4-phenoxybenzylidene)thiazolidin-3...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed