BDBM50214534 4-[5-(4-carboxymethoxybenzylidene)-2,4-dioxothiazolidin-3-yl]methylbenzoic acid::CHEMBL392380

SMILES OC(=O)COc1ccc(\C=C2/SC(=O)N(Cc3ccc(cc3)C(O)=O)C2=O)cc1

InChI Key InChIKey=HGHPGPKDIMQMJQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50214534   

TargetLow molecular weight phosphotyrosine protein phosphatase(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50214534(4-[5-(4-carboxymethoxybenzylidene)-2,4-dioxothiazo...)
Affinity DataIC50: 1.64E+6nMAssay Description:Inhibition of human low molecular weight Protein-tyrosine phosphatase IF2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50214534(4-[5-(4-carboxymethoxybenzylidene)-2,4-dioxothiazo...)
Affinity DataIC50: 8.50E+4nMAssay Description:Inhibition of human protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50214534(4-[5-(4-carboxymethoxybenzylidene)-2,4-dioxothiazo...)
Affinity DataIC50: 2.19E+5nMAssay Description:Inhibition of human low molecular weight Protein-tyrosine phosphatase IF1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Baker's yeast)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50214534(4-[5-(4-carboxymethoxybenzylidene)-2,4-dioxothiazo...)
Affinity DataIC50: 4.50E+5nMAssay Description:Inhibition of Saccharomyces cerevisiae low molecular weight Protein-tyrosine phosphatase Ltp1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed