BDBM50215029 (2S)-6-amino-N-benzyl-2-[(4R)-3-oxo-4-[(phenylacetyl)amino]-3,4,5,10-tetrahydroazepino[3,4-b]indol-2(1H)-yl]hexanamide::CHEMBL227212

SMILES NCCCC[C@H](N1Cc2[nH]c3ccccc3c2C[C@@H](NC(=O)Cc2ccccc2)C1=O)C(=O)NCc1ccccc1

InChI Key InChIKey=FGKNVWQWKFERAE-UHFFFAOYSA-N

Data  8 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50215029   

TargetSomatostatin receptor type 2(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50215029((2S)-6-amino-N-benzyl-2-[(4R)-3-oxo-4-[(phenylacet...)
Affinity DataIC50: 83nMAssay Description:Displacement of [125I][Leu8-D-Trp22, Tyr25]-SRIF28 from human SST2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 3(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50215029((2S)-6-amino-N-benzyl-2-[(4R)-3-oxo-4-[(phenylacet...)
Affinity DataIC50: 251nMAssay Description:Displacement of [125I][Leu8-D-Trp22, Tyr25]-SRIF28 from human SST3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50215029((2S)-6-amino-N-benzyl-2-[(4R)-3-oxo-4-[(phenylacet...)
Affinity DataEC50:  13nMAssay Description:Agonist activity at human SST5 receptor expressed in CHOK1 cells assessed as effect on forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50215029((2S)-6-amino-N-benzyl-2-[(4R)-3-oxo-4-[(phenylacet...)
Affinity DataIC50: 1.20nMAssay Description:Displacement of [125I][Leu8-D-Trp22, Tyr25]-SRIF28 from human SST5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 1(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50215029((2S)-6-amino-N-benzyl-2-[(4R)-3-oxo-4-[(phenylacet...)
Affinity DataIC50: 233nMAssay Description:Displacement of [125I][Leu8-D-Trp22, Tyr25]-SRIF28 from human SST1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 4(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50215029((2S)-6-amino-N-benzyl-2-[(4R)-3-oxo-4-[(phenylacet...)
Affinity DataIC50: 3.30nMAssay Description:Displacement of [125I][Leu8-D-Trp22, Tyr25]-SRIF28 from human SST4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50215029((2S)-6-amino-N-benzyl-2-[(4R)-3-oxo-4-[(phenylacet...)
Affinity DataIC50: 1.20nMAssay Description:Agonist activity at human SST5 receptor expressed in CHOK1 cells assessed as effect on forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 4(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50215029((2S)-6-amino-N-benzyl-2-[(4R)-3-oxo-4-[(phenylacet...)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human SSTR4 by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50215029((2S)-6-amino-N-benzyl-2-[(4R)-3-oxo-4-[(phenylacet...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human SSTR5 by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed