BDBM50215221 (R)-1-(2,6-difluorobenzyl)-6-(4-chlorobenzyl)-3-(2-(methylamino)-2-phenylethyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine-2,4(1H,3H)-dione::CHEMBL392709

SMILES CN[C@@H](Cn1c(=O)c2CN(Cc3ccc(Cl)cc3)CCc2n(Cc2c(F)cccc2F)c1=O)c1ccccc1

InChI Key InChIKey=JLFBHKWEJXWJSJ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50215221   

TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50215221((R)-1-(2,6-difluorobenzyl)-6-(4-chlorobenzyl)-3-(2...)
Affinity DataKi:  45nMAssay Description:Displacement of [125I]His5,D-Tyr6]GnRH from human cloned GnRH receptor transfected in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed