BDBM50215428 2-[6-(3-aminophenyl)-5-chloro-3-(cyclobutylamino)-2-oxo-1,2-dihydropyrazin-1-yl]-N-[(4-carbamimidoyl-2,3,5,6-tetrafluorophenyl)methyl]acetamide::CHEMBL230764

SMILES NC(=N)c1c(F)c(F)c(CNC(=O)Cn2c(c(Cl)nc(NC3CCC3)c2=O)-c2cccc(N)c2)c(F)c1F

InChI Key InChIKey=RDSBBUCRKDZPJU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50215428   

TargetCoagulation factor VII(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215428(2-[6-(3-aminophenyl)-5-chloro-3-(cyclobutylamino)-...)
Affinity DataIC50: 5.48E+3nMAssay Description:Inhibition of factor 7aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215428(2-[6-(3-aminophenyl)-5-chloro-3-(cyclobutylamino)-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215428(2-[6-(3-aminophenyl)-5-chloro-3-(cyclobutylamino)-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of factor 2aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed