BDBM50215438 (E)-N-((5-amino-2,3-dihydrobenzo[f][1,4]thiazepin-8-yl)methyl)-2-(6-(3-aminophenyl)-5-chloro-3-(cyclobutylamino)-2-oxopyrazin-1(2H)-yl)acetamide::CHEMBL388438

SMILES Nc1cccc(c1)-c1c(Cl)nc(NC2CCC2)c(=O)n1CC(=O)NCc1ccc2c(SCCN=C2N)c1

InChI Key InChIKey=DAJGBJRYEALKQA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50215438   

TargetProthrombin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215438((E)-N-((5-amino-2,3-dihydrobenzo[f][1,4]thiazepin-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of factor 2aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215438((E)-N-((5-amino-2,3-dihydrobenzo[f][1,4]thiazepin-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215438((E)-N-((5-amino-2,3-dihydrobenzo[f][1,4]thiazepin-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of factor 7aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed