BDBM50215718 (2S,3R)-methyl 1-(3-chloro-4-cyano-2-methylphenylsulfonyl)-3-hydroxypyrrolidine-2-carboxylate::CHEMBL234394

SMILES COC(=O)[C@@H]1[C@H](O)CCN1S(=O)(=O)c1ccc(C#N)c(Cl)c1C

InChI Key InChIKey=SFJHXIKHAFLZTL-UHFFFAOYSA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50215718   

TargetAndrogen receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50215718((2S,3R)-methyl 1-(3-chloro-4-cyano-2-methylphenyls...)
Affinity DataKi:  36nMAssay Description:Displacement of [3H]DHT from human androgen receptor in MDA453 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Mouse)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50215718((2S,3R)-methyl 1-(3-chloro-4-cyano-2-methylphenyls...)
Affinity DataIC50: 278nMAssay Description:Antagonist activity at androgen receptor in mouse C2C12 cells by receptor transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Mouse)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50215718((2S,3R)-methyl 1-(3-chloro-4-cyano-2-methylphenyls...)
Affinity DataEC50: >3.00E+3nMAssay Description:Agonist activity at androgen receptor in mouse C2C12 cells by receptor transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed