BDBM50215778 1-(4-((2-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)carbamoyl)phenylamino)methyl)pyridin-2-yl)-3-phenylurea::CHEMBL397345

SMILES FC1(F)Oc2ccc(NC(=O)c3ccccc3NCc3ccnc(NC(=O)Nc4ccccc4)c3)cc2O1

InChI Key InChIKey=BOPCXEIMMJMHTF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50215778   

TargetMast/stem cell growth factor receptor Kit(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215778(1-(4-((2-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)ca...)
Affinity DataIC50: 87nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215778(1-(4-((2-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)ca...)
Affinity DataIC50: 39nMAssay Description:Inhibition of b-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed