BDBM50215794 CHEMBL246423::N-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-2-((2-(methylsulfonamido)pyridin-4-yl)methylamino)benzamide

SMILES CS(=O)(=O)Nc1cc(CNc2ccccc2C(=O)Nc2ccc3OC(F)(F)Oc3c2)ccn1

InChI Key InChIKey=YZNNUIOSLHHWJF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50215794   

TargetSerine/threonine-protein kinase B-raf(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215794(N-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-2-((2-(me...)
Affinity DataIC50: 594nMAssay Description:Inhibition of b-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215794(N-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-2-((2-(me...)
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed