BDBM50215940 CHEMBL53559

SMILES COc1cccc(Cn2cc(C)c3ccc(cc23)C(=O)Nc2c(Cl)cncc2Cl)c1

InChI Key InChIKey=MPPSPPDSBGNALD-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50215940   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50215940(CHEMBL53559)
Affinity DataIC50: 60nMAssay Description:Inhibitory activity against Phosphodiesterase type IV (PDE4) obtained from guinea-pig macrophage was evaluatedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50215940(CHEMBL53559)
Affinity DataKi:  75nMAssay Description:Binding affinity against PDE4 was determined using [3H]- rolipram in guinea pig brain membrane binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2018
Entry Details Article
PubMed