BDBM50216177 CHEMBL230349::N-[(1S)-1-benzyl-2-hydroxyethyl]-2-[(cyclopropylmethyl)amino]-6-[methyl(methylsulfonyl)amino]isonicotinamide

SMILES CN(c1cc(cc(NCC2CC2)n1)C(=O)N[C@H](CO)Cc1cc(F)cc(F)c1)S(C)(=O)=O

InChI Key InChIKey=ACFXYVAYTWMZGA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50216177   

TargetBeta-secretase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50216177(N-[(1S)-1-benzyl-2-hydroxyethyl]-2-[(cyclopropylme...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of BACE1 by ECL assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed