BDBM50216835 (R)-ethyl 5-(1-(hydroxyamino)-1-oxo-6-phenylhexan-3-yl)-1,2,4-oxadiazole-3-carboxylate::CHEMBL229375

SMILES CCOC(=O)c1noc(n1)[C@H](CCCc1ccccc1)CC(=O)NO

InChI Key InChIKey=ZPTQFUMRMHOLBG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50216835   

Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216835((R)-ethyl 5-(1-(hydroxyamino)-1-oxo-6-phenylhexan-...)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216835((R)-ethyl 5-(1-(hydroxyamino)-1-oxo-6-phenylhexan-...)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of human procollagen C-proteinase expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216835((R)-ethyl 5-(1-(hydroxyamino)-1-oxo-6-phenylhexan-...)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of human MMP2 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216835((R)-ethyl 5-(1-(hydroxyamino)-1-oxo-6-phenylhexan-...)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed