BDBM50216859 CHEMBL442232::{2-(hydroxymethyl)-5-[5-methyl-3-(2-methylpropyl)hexylidene]-4-oxo-1,3-dioxolan-2-yl}methyl 2,2-dimethylpropanoate

SMILES CC(C)CC(C\C=C1\OC(CO)(COC(=O)C(C)(C)C)OC1=O)CC(C)C

InChI Key InChIKey=FNAVULFGMYGNQE-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50216859   

TargetProtein kinase C delta type(Mouse)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50216859({2-(hydroxymethyl)-5-[5-methyl-3-(2-methylpropyl)h...)
Affinity DataKi:  0.820nMAssay Description:Displacement of [3H]PDBu from mouse wild type C1b domain of PKCdelta expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C delta type(Mouse)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50216859({2-(hydroxymethyl)-5-[5-methyl-3-(2-methylpropyl)h...)
Affinity DataKi:  4.31nMAssay Description:Binding affinity to mouse wild-type PKCdelta C1a expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Mouse)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50216859({2-(hydroxymethyl)-5-[5-methyl-3-(2-methylpropyl)h...)
Affinity DataKi:  6.41nMAssay Description:Displacement of [3H]PDBu from mouse recombinant PKCalpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C delta type(Mouse)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50216859({2-(hydroxymethyl)-5-[5-methyl-3-(2-methylpropyl)h...)
Affinity DataKi:  1.57E+3nMAssay Description:Binding affinity to mouse PKC delta C1a Q27E mutant expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C delta type(Mouse)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50216859({2-(hydroxymethyl)-5-[5-methyl-3-(2-methylpropyl)h...)
Affinity DataKi:  2.51E+3nMAssay Description:Displacement of [3H]PDBu from mouse PKCdelta C1b Q27E mutant expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed