BDBM50217186 5-((4-aminopiperidin-1-yl)methyl)-N-(3-chloro-4-(pyrazin-2-ylmethoxy)phenyl)pyrrolo[1,2-f][1,2,4]triazin-4-amine::CHEMBL248321

SMILES NC1CCN(Cc2ccn3ncnc(Nc4ccc(OCc5cnccn5)c(Cl)c4)c23)CC1

InChI Key InChIKey=YNFCRDTVTDENKG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50217186   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50217186(5-((4-aminopiperidin-1-yl)methyl)-N-(3-chloro-4-(p...)
Affinity DataIC50: 26nMAssay Description:Inhibition of human recombinant HER2 expressed in insect Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50217186(5-((4-aminopiperidin-1-yl)methyl)-N-(3-chloro-4-(p...)
Affinity DataIC50: 32nMAssay Description:Inhibition of human recombinant EGFR expressed in insect Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed