BDBM50217208 5-((1,4-diazepan-1-yl)methyl)-N-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-6-methoxypyrrolo[1,2-f][1,2,4]triazin-4-amine::CHEMBL247711

SMILES COc1cn2ncnc(Nc3ccc4n(Cc5cccc(F)c5)ncc4c3)c2c1CN1CCCNCC1

InChI Key InChIKey=YDACLKUOFPGAGO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50217208   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50217208(5-((1,4-diazepan-1-yl)methyl)-N-(1-(3-fluorobenzyl...)
Affinity DataIC50: 170nMAssay Description:Inhibition of human recombinant HER2 expressed in insect Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50217208(5-((1,4-diazepan-1-yl)methyl)-N-(1-(3-fluorobenzyl...)
Affinity DataIC50: 190nMAssay Description:Inhibition of human recombinant EGFR expressed in insect Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed