BDBM50217581 4-(4-(1-isopropylpiperidin-4-yloxy)benzyl)morpholine::4-[4-(1-Isopropyl-piperidin-4-yloxy)-benzyl]-morpholine::CHEMBL194092

SMILES CC(C)N1CCC(CC1)Oc1ccc(CN2CCOCC2)cc1

InChI Key InChIKey=AYEMHSJPBSPTSA-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50217581   

TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50217581(4-[4-(1-Isopropyl-piperidin-4-yloxy)-benzyl]-morph...)
Affinity DataKi:  2.10nMAssay Description:Binding affinity to human histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50217581(4-[4-(1-Isopropyl-piperidin-4-yloxy)-benzyl]-morph...)
Affinity DataKi:  2.10nMAssay Description:Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells after 1 hr by fluid scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50217581(4-[4-(1-Isopropyl-piperidin-4-yloxy)-benzyl]-morph...)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50217581(4-[4-(1-Isopropyl-piperidin-4-yloxy)-benzyl]-morph...)
Affinity DataKi:  2.14nMAssay Description:Mean binding affinity for human H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed