BDBM50218087 CHEMBL402060::N-((S)-1-(2-(4-((3R,4S)-3-(4-chlorophenyl)-1-isopropylpyrrolidine-4-carbonyl)piperazin-1-yl)-5-(trifluoromethyl)phenyl)-3-methylbutyl)azetidine-3-carboxamide

SMILES CC(C)C[C@H](NC(=O)C1CNC1)c1cc(ccc1N1CCN(CC1)C(=O)[C@@H]1CN(C[C@H]1c1ccc(Cl)cc1)C(C)C)C(F)(F)F

InChI Key InChIKey=JBMFMWRIVIDCKM-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50218087   

TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218087(N-((S)-1-(2-(4-((3R,4S)-3-(4-chlorophenyl)-1-isopr...)
Affinity DataEC50:  6.60nMAssay Description:Agonist activity at human MC4R expressed in HEK293 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50218087(N-((S)-1-(2-(4-((3R,4S)-3-(4-chlorophenyl)-1-isopr...)
Affinity DataKi:  18nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed