BDBM50218231 4-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-4-(4-fluorophenyl)pyrrolidin-1-yl)-1-methyl-1H-pyrrol-2(5H)-one::CHEMBL251557

SMILES C[C@@H](O[C@@H]1CN(C[C@H]1c1ccc(F)cc1)C1=CC(=O)N(C)C1)c1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=DGBAJNCOLJSECV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50218231   

TargetSubstance-P receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50218231(4-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)pheny...)
Affinity DataIC50: 0.120nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed