BDBM50218449 4-[2-(4-chloro-benzylsulfanyl)-5,7,7,10,10-pentamethyl-7,8,9,10-tetrahydro-5H-5,13-diaza-benzo[4,5]cyclohepta[1,2-b]naphthalen-12-yl]-benzoic acid::CHEMBL438857

SMILES CN1c2ccc(SCc3ccc(Cl)cc3)cc2N=C(c2ccc(cc2)C(O)=O)c2cc3c(cc12)C(C)(C)CCC3(C)C

InChI Key InChIKey=RYXITAYATKODHN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50218449   

TargetRetinoic acid receptor RXR-alpha(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50218449(4-[2-(4-chloro-benzylsulfanyl)-5,7,7,10,10-pentame...)
Affinity DataIC50: 670nMAssay Description:Inhibition of 9-cis-retinoic acid-induced RXRalpha transactivationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50218449(4-[2-(4-chloro-benzylsulfanyl)-5,7,7,10,10-pentame...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of LG-100268-induced RXRalpha transactivationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed