BDBM50218513 3-(4-{[benzyl-(2-hydroxyethyl)amino]methyl}phenyl)-6,7-dimethoxychromen-2-one::CHEMBL396247

SMILES COc1cc2cc(-c3ccc(CN(CCO)Cc4ccccc4)cc3)c(=O)oc2cc1OC

InChI Key InChIKey=VFAABMDLNHZKGL-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50218513   

TargetCholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50218513(3-(4-{[benzyl-(2-hydroxyethyl)amino]methyl}phenyl)...)
Affinity DataIC50: 3.51E+4nMAssay Description:Inhibition of human recombinant BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50218513(3-(4-{[benzyl-(2-hydroxyethyl)amino]methyl}phenyl)...)
Affinity DataIC50: 49nMAssay Description:Inhibition of human recombinant AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50218513(3-(4-{[benzyl-(2-hydroxyethyl)amino]methyl}phenyl)...)
Affinity DataKi:  11nMAssay Description:Inhibition of recombinant human AChE assessed as hydrolysis of acetylthiocholine by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed