BDBM50218847 4-cyclopropylamino-6-[(pyridin-3-ylmethyl)-amino]-[1,7]naphthyridine-3-carbonitrile::CHEMBL446633

SMILES N#Cc1cnc2cnc(NCc3cccnc3)cc2c1NC1CC1

InChI Key InChIKey=OTWLNXLUULJDHT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50218847   

TargetEpidermal growth factor receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50218847(4-cyclopropylamino-6-[(pyridin-3-ylmethyl)-amino]-...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of EGFR kinase autophosphorylation in A431 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed