BDBM50219012 CHEMBL359035

SMILES COc1ncc(C(=O)Nc2c(Cl)c[n+]([O-])cc2Cl)c2cc(oc12)C1(CCN(CC1)C(=O)OC(C)(C)C)OC

InChI Key InChIKey=LYJGBGQLQMRKKF-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50219012   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Celltech R&D

Curated by ChEMBL

LigandBDBM50219012(CHEMBL359035)Copy SMILESCopy InChI

Affinity DataIC50: 48nMAssay Description:Inhibition of human phosphodiesterase 4 from U937 cellsMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/10/2018
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rat)
Celltech R&D

Curated by ChEMBL

LigandBDBM50219012(CHEMBL359035)Copy SMILESCopy InChI

Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of rolipram binding to rat brainMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/10/2018
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL