BDBM50219269 (5-(aminomethyl)-2-(8-methoxy-2-(trifluoromethyl)quinolin-5-yl)oxazol-4-yl)(4-(4,6-dimethoxypyrimidin-2-yl)piperazin-1-yl)methanone::CHEMBL401345

SMILES COc1cc(OC)nc(n1)N1CCN(CC1)C(=O)c1nc(oc1CN)-c1ccc(OC)c2nc(ccc12)C(F)(F)F

InChI Key InChIKey=JQWUZRQDRJVXDJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50219269   

TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50219269((5-(aminomethyl)-2-(8-methoxy-2-(trifluoromethyl)q...)
Affinity DataIC50: 970nMAssay Description:Inhibition of PDE11More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50219269((5-(aminomethyl)-2-(8-methoxy-2-(trifluoromethyl)q...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of PDE4BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50219269((5-(aminomethyl)-2-(8-methoxy-2-(trifluoromethyl)q...)
Affinity DataIC50: 760nMAssay Description:Inhibition of PDE10More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed