BDBM50219275 CHEMBL249691::tert-butyl 4-(5-(aminomethyl)-2-(8-methoxy-2-(trifluoromethyl)quinolin-5-yl)oxazole-4-carbonyl)piperazine-1-carboxylate

SMILES COc1ccc(-c2nc(C(=O)N3CCN(CC3)C(=O)OC(C)(C)C)c(CN)o2)c2ccc(nc12)C(F)(F)F

InChI Key InChIKey=PYQKWFDIHMQDQJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50219275   

TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50219275(tert-butyl 4-(5-(aminomethyl)-2-(8-methoxy-2-(trif...)
Affinity DataIC50: 600nMAssay Description:Inhibition of PDE11More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50219275(tert-butyl 4-(5-(aminomethyl)-2-(8-methoxy-2-(trif...)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of PDE4BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50219275(tert-butyl 4-(5-(aminomethyl)-2-(8-methoxy-2-(trif...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of PDE10More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed