BDBM50219334 CHEMBL267102

SMILES Nc1nc(O)c2nc(Br)n(C3CCCc4cccc(Br)c34)c2n1

InChI Key InChIKey=QLRAFBKUHQNNFZ-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50219334   

TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Palack£

Curated by ChEMBL

LigandBDBM50219334(CHEMBL267102)Copy SMILESCopy InChI

Affinity DataIC50: 1.31E+3nMAssay Description:Inhibition of human recombinant PDE7A using cAMP as substrate incubated for 20 mins measured by Kinase Glo reagent based microplate reader assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
3/28/2022
Entry Details Article
Copy BDB DOIPubMed
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TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A/cAMP-specific 3',5'-cyclic phosphodiesterase 7B(Human)
Celltech R&D

Curated by ChEMBL

LigandBDBM50219334(CHEMBL267102)Copy SMILESCopy InChI

Affinity DataIC50: 1.31E+3nMAssay Description:Inhibition of human Phosphodiesterase 7 of HUT-78 cellsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
10/31/2018
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL