BDBM50219377 1-((1r,4r)-4-morpholinocyclohexyl)-3-(2-(thiophen-3-ylmethyl)-1H-benzo[d]imidazol-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine::CHEMBL249082

SMILES Nc1ncnc2n(nc(-c3ccc4nc(Cc5ccsc5)[nH]c4c3)c12)[C@H]1CC[C@@H](CC1)N1CCOCC1

InChI Key InChIKey=AJYKKQGFOFSZLL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50219377   

TargetInsulin-like growth factor 1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219377(1-((1r,4r)-4-morpholinocyclohexyl)-3-(2-(thiophen-...)
Affinity DataIC50: 32nMAssay Description:Inhibition of human IGF1R expressed in Sf21 cells by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219377(1-((1r,4r)-4-morpholinocyclohexyl)-3-(2-(thiophen-...)
Affinity DataIC50: 84nMAssay Description:Inhibition IGF1R phosphorylation in human MiaPaCa2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed