BDBM50219385 1-((1r,4r)-4-morpholinocyclohexyl)-3-(2-phenyl-1H-benzo[d]imidazol-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine::CHEMBL249296

SMILES Nc1ncnc2n(nc(-c3ccc4nc([nH]c4c3)-c3ccccc3)c12)[C@H]1CC[C@@H](CC1)N1CCOCC1

InChI Key InChIKey=AEPPFJZPUGRZEO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50219385   

TargetInsulin-like growth factor 1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219385(1-((1r,4r)-4-morpholinocyclohexyl)-3-(2-phenyl-1H-...)
Affinity DataIC50: 176nMAssay Description:Inhibition of human IGF1R expressed in Sf21 cells by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219385(1-((1r,4r)-4-morpholinocyclohexyl)-3-(2-phenyl-1H-...)
Affinity DataIC50: 787nMAssay Description:Inhibition IGF1R phosphorylation in human MiaPaCa2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed