BDBM50219625 CHEMBL247606::N-(4-(2-fluoro-3-(trifluoromethoxy)phenyl)thiazol-2-yl)-4-(pyrimidin-4-ylamino)benzamide

SMILES Fc1c(OC(F)(F)F)cccc1-c1csc(NC(=O)c2ccc(Nc3ccncn3)cc2)n1

InChI Key InChIKey=OYFQARLFQPKSIY-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50219625   

TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50219625(N-(4-(2-fluoro-3-(trifluoromethoxy)phenyl)thiazol-...)
Affinity DataEC50:  32nMAssay Description:Agonist activity at human TPOr expressed in BaF3 cells by reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50219625(N-(4-(2-fluoro-3-(trifluoromethoxy)phenyl)thiazol-...)
Affinity DataEC50:  32nMAssay Description:Agonist activity at TPO receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed