BDBM50219645 CHEMBL248042::N-(4-(2-fluoro-3-(trifluoromethyl)phenyl)thiazol-2-yl)-4-(6-((2-methoxyethyl)(methyl)amino)pyrimidin-4-ylamino)benzamide

SMILES COCCN(C)c1cc(Nc2ccc(cc2)C(=O)Nc2nc(cs2)-c2cccc(c2F)C(F)(F)F)ncn1

InChI Key InChIKey=ZJILDGXZYULAJU-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50219645   

TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50219645(N-(4-(2-fluoro-3-(trifluoromethyl)phenyl)thiazol-2...)
Affinity DataEC50:  84nMAssay Description:Agonist activity at human TPOr expressed in BaF3 cells by reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed