BDBM50219705 CHEMBL246428::N-(3-(4-fluoro-3-(trifluoromethyl)phenyl)-1,2,4-thiadiazol-5-yl)-4-(6-((2-methoxyethyl)(methyl)amino)pyrimidin-4-ylamino)benzamide

SMILES COCCN(C)c1cc(Nc2ccc(cc2)C(=O)Nc2nc(ns2)-c2ccc(F)c(c2)C(F)(F)F)ncn1

InChI Key InChIKey=RNDKLAJBVAMORT-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50219705   

TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50219705(N-(3-(4-fluoro-3-(trifluoromethyl)phenyl)-1,2,4-th...)
Affinity DataEC50:  130nMAssay Description:Agonist activity at human TPOr expressed in BaF3 cells by reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed