BDBM50219827 CHEMBL42479

SMILES COc1ccc(C(=O)Nc2ccncc2Cl)c2ccc(nc12)C(F)(F)F

InChI Key InChIKey=KWMBPADFEBNIHV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50219827   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rat)
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50219827(CHEMBL42479)
Affinity DataIC50: 110nMAssay Description:Inhibition of rolipram binding to PDE4 of rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2018
Entry Details Article
PubMed
LigandPNGBDBM50219827(CHEMBL42479)
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of PDE4 in Homo sapiens (human) U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

LigandPNGBDBM50219827(CHEMBL42479)
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of Phosphodiesterase 4 from human U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2018
Entry Details Article
PubMed