BDBM50220086 4-(7-methylpyrido[2,3-d]pyrimidin-2-yl)benzonitrile::CHEMBL239619

SMILES Cc1ccc2cnc(nc2n1)-c1ccc(cc1)C#N

InChI Key InChIKey=NTNUGRSOASXIMN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50220086   

TargetMetabotropic glutamate receptor 5(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220086(4-(7-methylpyrido[2,3-d]pyrimidin-2-yl)benzonitril...)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonistic activity at rat mGluR5 expressed in CHO cells assessed as inhibition of quisqualate stimulated calcium mobilization by FLIPR technologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed