BDBM50220089 7-methyl-2-(3-(methylsulfonyl)phenyl)pyrido[2,3-d]pyrimidine::CHEMBL236379

SMILES Cc1ccc2cnc(nc2n1)-c1cccc(c1)S(C)(=O)=O

InChI Key InChIKey=WDWJSGSTCCAOLT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50220089   

TargetMetabotropic glutamate receptor 5(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220089(7-methyl-2-(3-(methylsulfonyl)phenyl)pyrido[2,3-d]...)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonistic activity at rat mGluR5 expressed in CHO cells assessed as inhibition of quisqualate stimulated calcium mobilization by FLIPR technologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed